Fig. 2
- ID
 - ZDB-FIG-180323-25
 - Publication
 - Prats et al., 2017 - Modelling acrylamide acute neurotoxicity in zebrafish larvae
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 ACR reduces presynaptic nerve terminals in zebrafish larvae. At the neuromuscular junctions (NMJ) of the trunk, ACR-exposed larvae exhibit an strong reduction in the labelling of synaptic vesicle glycoprotein 2a (marker of synaptic terminals of the spinal motor neurons), whereas the α-bungarotoxin labelling (post-synaptic marker at the NMJ) labelling remains unaltered. Detail of the trunk, in lateral view, of control (a–c) and ACR-treated (d–f) larvae after co-labelling with α -bungarotoxin Alexa Fluor 488 conjugate (a,d) and SV2 antibody. The co-localization of the pre-synaptic and post-synaptic markers of NMJ is also showed (c,f). Scale bar: 100 μm.  |