ZFIN Image: Prats et al., 2017, Fig. 2

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Figure Caption

Fig. 2

ACR reduces presynaptic nerve terminals in zebrafish larvae. At the neuromuscular junctions (NMJ) of the trunk, ACR-exposed larvae exhibit an strong reduction in the labelling of synaptic vesicle glycoprotein 2a (marker of synaptic terminals of the spinal motor neurons), whereas the α-bungarotoxin labelling (post-synaptic marker at the NMJ) labelling remains unaltered. Detail of the trunk, in lateral view, of control (a–c) and ACR-treated (d–f) larvae after co-labelling with α -bungarotoxin Alexa Fluor 488 conjugate (a,d) and SV2 antibody. The co-localization of the pre-synaptic and post-synaptic markers of NMJ is also showed (c,f). Scale bar: 100 μm.

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