FIGURE

Fig. 2

ID

ZDB-FIG-180122-19

Publication

Kim et al., 2017 - Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality

Other Figures

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Fig. 2

Laterality of heart was disrupted in cldn5a morphants.

(A—H) Visualization of a heart by in situ hybridization of cmlc1 in 30 hpf embryos. Representative images of control morphants (A), cldn5a morphants (B), DFC cldn5a morphants (C), and yolk cldn5a morphants (D). (E) Stacked bar graph (blue; normal, orange; middle, grey; reversed, control morphants; n = 45, cldn5a morphants; n = 33, DFC control morphants; n = 71, DFC cldn5a morphants; n = 37, yolk control morphants; n = 25, yolk cldn5a morphants; n = 31). Representative images of control morphants with mCherry (F), cldn5a morphants with mCherry (G), cldn5a morphants with mCherry-cldn5a (H). (I) Stacked bar graph (blue; normal, orange; middle, grey; reversed, control morphants with mCherry; n = 132, cldn5a morphants with mCherry; n = 111, cldn5a morphants with mCherry-cldn5a; n = 115). * depicts p < 0.05.

Expression Data

Gene:	cmlc1
Fish:	TU TU + MO3-cldn5a
Knockdown Reagent:	MO3-cldn5a
Anatomical Term:	heart tube
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU + MO3-cldn5a
Knockdown Reagent:	MO3-cldn5a
Observed In:	determination of heart left/right asymmetry heart tube
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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