Gene

cmlc1

ID
ZDB-GENE-030522-1
Name
cardiac myosin light chain-1
Symbol
cmlc1 Nomenclature History
Previous Names
  • laz (1)
  • lazy susan (1)
  • zgc:103441
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in heart contraction; heart morphogenesis; and myofibril assembly. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Is expressed in heart primordium; mesoderm; pericardial region; and somite. Orthologous to human MYL4 (myosin light chain 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cmlc1 Human Ortholog
No data available
Associated With cmlc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002048 EF-hand domain
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length EF-hand domain EF-hand domain pair
UniProtKB:Q9PTR0 65
UniProtKB:Q5XJC3 196
UniProtKB:B0R0F7 196
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations