header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-180104-52
Xia et al., 2017 - New role of LRP5, associated with non-syndromic autosomal recessive hereditary hearing loss. Human Mutation   38(10):1421-1431 Full text @ Hum. Mutat.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Protruding-mouth

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
axin2 WT standard conditions Protruding-mouth whole organism RTPCR
WT + MO5-lrp5 + MO6-lrp5 standard conditions Protruding-mouth whole organism RTPCR
lef1 WT standard conditions Protruding-mouth whole organism RTPCR
WT + MO5-lrp5 + MO6-lrp5 standard conditions Protruding-mouth whole organism RTPCR
myca WT standard conditions Protruding-mouth whole organism RTPCR
WT + MO5-lrp5 + MO6-lrp5 standard conditions Protruding-mouth whole organism RTPCR
sox2 WT standard conditions Protruding-mouth whole organism RTPCR
WT + MO5-lrp5 + MO6-lrp5 standard conditions Protruding-mouth whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO5-lrp5 + MO6-lrp5 standard conditions Protruding-mouth otic vesicle cell population proliferation decreased occurrence, abnormal
Protruding-mouth whole organism axin2 expression decreased amount, abnormal
Protruding-mouth whole organism myca expression decreased amount, abnormal
Protruding-mouth whole organism sox2 expression decreased amount, abnormal
Protruding-mouth whole organism lef1 expression decreased amount, abnormal
Full text @ Hum. Mutat.