ZFIN ID: ZDB-FIG-180104-50
Xia et al., 2017 - New role of LRP5, associated with non-syndromic autosomal recessive hereditary hearing loss. Human Mutation   38(10):1421-1431 Full text @ Hum. Mutat.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Day 5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO5-lrp5 + MO6-lrp5 standard conditions Protruding-mouth inner ear morphology, abnormal
Protruding-mouth otic vesicle decreased size, abnormal
Protruding-mouth otolith absent, abnormal
Protruding-mouth otolith decreased amount, abnormal
s356tTg + MO5-lrp5 + MO6-lrp5 standard conditions Long-pec neuromast hair cell decreased amount, abnormal
Long-pec neuromast support cell decreased amount, abnormal
Protruding-mouth neuromast decreased size, abnormal
Protruding-mouth posterior lateral line neuromast decreased amount, abnormal
Day 5 neuromast hair cell stereocilium decreased amount, abnormal
Day 5 neuromast hair cell stereocilium decreased length, abnormal
Day 5 neuromast hair cell stereocilium decreased thickness, abnormal
Full text @ Hum. Mutat.