FIGURE

Fig. 2

ID
ZDB-FIG-171113-47
Publication
Kotb et al., 2016 - Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin
Other Figures
All Figure Page
Back to All Figure Page
Fig. 2

APOL1 expression in human and zebrafish glomeruli.

The expression of APOL1 in podocytes is shown by double staining with an antibody against APOL1 and an antibody against the podocyte-specific proteins synaptopodin and nephrin (A-H). The regions in panel D and H labeled by arrows are shown in higher magnifications (insets). Similar to the human kidney, zApoL1 colocalizes with zNephrin in the zebrafish glomerulus (L). Panel M shows the localization of zApoL1 in podocytes (red circles) and in endothelial cells (green circles) by immunoelectron microscopy. Panel N shows the control reaction (secondary antibody only). Scale bars represent 20 μm (A-L) and 1 μm (M-N).

Expression Data
Genes:
Antibody:
Fish:
Anatomical Terms:
Stage: Day 4

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One