FIGURE
Fig. 8
Fig. 8
zApoL1 KD rescue in zebrafish larvae by human Nephrin mRNA. The rescue of the nephrin KD by human Nephrin mRNA (hmRNA) resulted in zebrafish larvae (CADE) without edema and with an intact filtration barrier (A). The KD of zApoL1 was rescued by co-injection of hmRNA resulting in zebrafish larvae without any phenotype (B). C shows the percentage of larvae with an edema after nephrin KD and rescue by hmRNA. The expression of the human mRNA was verified by RT-PCR as shown in D. We have used t-test for statistical analysis. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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