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ZFIN ID: ZDB-FIG-171011-14
Morrow et al., 2017 - tbx6l and tbx16 are redundantly required for posterior paraxial mesoderm formation during zebrafish embryogenesis. Developmental dynamics : an official publication of the American Association of Anatomists   246(10):759-769 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: 14-19 somites
PHENOTYPE:
Fish:
Observed In:
Stage Range: 14-19 somites to Prim-5

Fig. 3

tbx6l; tbx16 double mutants have an enlarged tail bud and lack tail somites. A–C′: Brightfield images of 24-hpf live wild-type (A, A′), tbx16 (spt) mutant (B,B′), and tbx6l; tbx16 double-mutant (C,C′) embryos. tbx6l single-mutant embryos are not shown here as they are indistinguishable from wild-type embryos (see Fig. 1F,G). Black dots in the magnified views (A′–C′) indicate morphologically visible tail somites. D–F: In situ hybridization for msgn1 at the 16-somite stage. Scale bar in A (for A–C) = 250 μm. Scale bar in A′ (for A′–C′) = 100 μm. Scale bar in F (for D–F) = 50 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
msgn1 WT standard conditions 14-19 somites paraxial mesoderm ISH
tbx16b104/b104 standard conditions 14-19 somites paraxial mesoderm ISH
tbx16lz35/z35; tbx16b104/b104 standard conditions 14-19 somites Not Detected paraxial mesoderm ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
tbx16b104/b104 standard conditions 14-19 somites paraxial mesoderm msgn1 expression decreased amount, abnormal
Prim-5 post-vent region somite present, normal
Prim-5 trunk somite absent, abnormal
tbx16lz35/z35; tbx16b104/b104 standard conditions 14-19 somites paraxial mesoderm msgn1 expression absent, abnormal
tbx16lz35/z35; tbx16b104/b104 standard conditions Prim-5 post-vent region somite absent, abnormal
tbx16lz35/z35; tbx16b104/b104 standard conditions Prim-5 tail bud increased size, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.