FIGURE

Fig. S3

ID
ZDB-FIG-171006-39
Publication
Du et al., 2014 - Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1
Other Figures
All Figure Page
Back to All Figure Page
Fig. S3

Setdb2 or Dvr1 knockdown and overexpression of dvr1 induce defects of cell polarity at the tail-bud stage. (A–D) Representative confocal images of notochord cells in control embryos (n=4 embryos, 80 cells), setdb2 morphants (n=4 embryos, 80 cells), dvr1 morphants (moATG) (n=4 embryos, 80 cells) and dvr1 mRNA overexpression embryos (n=4 embryos, 80 cells) co-injected at the one-cell stage with 100 pg mRNA coding for membrane-targeted RFP. Anterior is upwards. The boundaries of the notochord are marked with dotted white lines. (E-F) Length-width ratio (LWR) of notochord cells and mediolateral alignment (ML alignment) at the tail-bud stage were measured with ImageJ2X. The rose diagrams were drawn using Rose.NET. Scale bar: 20 μm. The statistical significance of difference is indicated by asterisks (**, P<0.01; ****, P<0.0001).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 392(2), Du, T.T., Xu, P.F., Dong, Z.W., Fan, H.B., Jin, Y., Dong, M., Chen, Y., Pan, W.J., Ren, R.B., Liu, T.X., Deng, M., Huang, Q.H., Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1, 233-44, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.