FIGURE

Fig. 6

ID

ZDB-FIG-170901-7

Publication

Gau et al., 2017 - An ancient neurotrophin receptor code; a single Runx/Cbfβ complex determines somatosensory neuron fate specification in zebrafish

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Fig. 6

Loss of runx or cbfb expression affects trk receptor expression in the RBs.

A-M, Colormetric in situ hybridization for trkA (A-D), trkB1 (E-H), and trkC1 (I-L) in runx1^W84X/W84X, runx3^w144/w144 and cbfb^w128/w128 mutants focusing on the RBs at 24hpf and 3dpf. M, Quantification of marker gene expression as % total RBs at 24hpf. Arrow, RBs. Scale bar: 100 μm. Embryos per condition (n = 3–12). *p<0.05, ***p<0.001. All error bars represent S.E.M.

Expression Data

Genes:	ntrk1 ntrk2a ntrk3a
Fish:	WT cbfb^w128/w128 (AB) runx1^hg1/hg1 runx3^w144/w144 (AB)
Anatomical Term:	Rohon-Beard neuron
Stage Range:	Prim-5 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cbfb^w128/w128 (AB) runx1^hg1/hg1 runx3^w144/w144 (AB)
Observed In:	Rohon-Beard neuron
Stage Range:	Prim-5 to Protruding-mouth

Phenotype Detail

Acknowledgments

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