FIGURE

Fig. S9

ID

ZDB-FIG-170830-15

Publication

Rasouli et al., 2017 - Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling

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Fig. S9

Myocardial specific nrg2a overexpression leads to an increase in cardiomyocyte proliferation

(a-d) 3D views (maximum intensity z-projections) of Tg(myl7:mVenus-gmnn) (a and c) or Tg(myl7:mVenus-gmnn);Tg(myl7:nrg2a-p2a-tdTomato) (b and d) hearts at 78 (a-b) and 96 (c-d) hpf. Proliferating cardiomyocytes are labeled in green; white and yellow dashed boxes outline the ventricular and atrial chambers, respectively; V: ventricle, At: atrium; scale bars, 50 μm. (e-f) Graphs showing the average number of proliferating cardiomyocytes per heart (e) and per ventricular or atrial (f) chamber at 78 and 96 hpf; N=9 hearts; values represent means ± SEM; * P≤ 0.05,** P≤ 0.01 by Student’s t-test.

Expression Data

Genes:	Tomato Venus
Fish:	ncv43Tg bns140Tg; ncv43Tg
Anatomical Terms:	atrial myocardium ventricular myocardium
Stage Range:	Protruding-mouth to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	bns140Tg; ncv43Tg
Observed In:	atrial myocardium cardiac muscle cell proliferation ventricular myocardium cardiac muscle cell proliferation
Stage Range:	Protruding-mouth to Day 4

Phenotype Detail

Acknowledgments

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