FIGURE

Fig. S2

ID

ZDB-FIG-170512-40

Publication

Keightley et al., 2017 - The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger

Other Figures

(all 9)

All Figure Page

Back to All Figure Page

Fig. S2

Depletion of definitive haemopoiesis in mne (supports Fig. 1b)

Whole-mount in situ hybridization showing: a. Erythromyeloid specification marked by gata1, lmo2 and pu.1 expression proceeds in mne;

b. HSC specification marked by runx1 and myb proceeds in mne.

c,d. At 72 and 96 hpf, HSCs are depleted in mne while O-dianisidine staining shows haemoglobinised erythrocyte abundance is unaffected;

e. Decreased numbers of cells expressing mpl and itga2b shows that thrombocytes are depleted in mne. Where head and tail images of the same embryo were spliced to maintain in-focus focal plane, a dashed line indicates the junction; panels a-e scale bar = 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.