Fig. S1
- ID
- ZDB-FIG-170512-39
- Publication
- Keightley et al., 2017 - The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger
- Other Figures
- (all 9)
- All Figure Page
- Back to All Figure Page
Marsanne is a temperature-sensitive zbtb11 mutant (supports Fig. 1b) a. Whole-mount in situ hybridization showing staining of mpx+ neutrophils and gross morphology demonstrates severity of the mne myeloid-failure phenotype and the overall dysmorphic phenotype of mne embryos varies with temperature. Grey arrows indicate neutrophils; scale bar = 200 μm; b. At lower temperature (21°C) neutrophil numbers are partly restored towards normal and at higher temperatures (33°C) the neutrophil deficiency is exacerbated. Left: n=14-16/group; Right: n=12-17/group; mean ±SD, twotailed unpaired t-test. |