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Fig. S1
Marsanne is a temperature-sensitive zbtb11 mutant (supports Fig. 1b)
a. Whole-mount in situ hybridization showing staining of mpx+ neutrophils and gross morphology demonstrates severity of the mne myeloid-failure phenotype and the overall dysmorphic phenotype of mne embryos varies with temperature. Grey arrows indicate neutrophils; scale bar = 200 μm;
b. At lower temperature (21°C) neutrophil numbers are partly restored towards normal and at higher temperatures (33°C) the neutrophil deficiency is exacerbated. Left: n=14-16/group; Right: n=12-17/group; mean ±SD, twotailed unpaired t-test.
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Full text @ Nat. Commun.