FIGURE

Fig. 6

ID
ZDB-FIG-170419-6
Publication
Ki et al., 2017 - Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors
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Fig. 6

Sunitinib promotes apoptosis of primary MPNST progression in transgenic fish expressing wild-type PDGFRA. (a–d) Histopathology after H&E staining of the DMSO- (a and b) or sunitinib- (c and d) treated MPNSTs. Black arrowheads show areas of MPNSTs (black scale bar=5mm). Proliferating cell nuclear antigen (e–h) and cleaved caspase-3 (i–l) stains of each condition for proliferation and apoptosis analysis, respectively. The right upper corner of each panel shows magnified stained areas.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Adult

Phenotype Detail
Acknowledgments
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