FIGURE

Fig. 7

ID

ZDB-FIG-161222-29

Publication

Tappeiner et al., 2016 - Inhibition of the TGFβ Pathway Enhances Retinal Regeneration in Adult Zebrafish

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Fig. 7

TUNEL positive cells in the zebrafish retina after exposure to MNU.

In uninjured zebrafish retina there are merely no TUNEL positive cells. Three days after exposure to 150 mg/l MNU, both the non-inhibited (0.1% dimethyl sulfide, DMSO) and the inhibited group (small molecule inhibitor SB431542) show a considerable amount of TUNEL positive cells (green) in the outer nuclear layer (ONL) and to a lesser degree in the inner nuclear layer (INL). Cell nuclei are stained with DAPI (blue). Scale bar indicates 50 μm. GC: ganglion cells.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by environment: N-methyl-N-nitrosourea chemical treatment by environment: N-methyl-N-nitrosourea
Observed In:	retinal outer nuclear layer apoptotic process
Stage:	Adult

Phenotype Detail

Acknowledgments

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