FIGURE
Fig. 4
- ID
- ZDB-FIG-161222-27
- Publication
- Tappeiner et al., 2016 - Inhibition of the TGF? Pathway Enhances Retinal Regeneration in Adult Zebrafish
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Fig. 4
H&E staining of zebrafish retinas before (uninjured) and after induction of retina degeneration with MNU. In the non-inhibited (0.1% dimethyl sulfide, DMSO) and inhibited group (small molecule inhibitor SB431542), a reduction of rod cells was observed starting at day 3. In the non-inhibited group the reduction of rod photoreceptors persisted until day 8, whereas in the group with the inhibited TGF? pathway (small molecule inhibitor SB431542) a rapid recovery was observed already at day 5. Scale bar indicates 50 ?m. GC: ganglion cells, INL: inner nuclear layer, ONL: outer nuclear layer, SB: SB431542 |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Conditions: | |
| Observed In: | |
| Stage: | Adult |
Phenotype Detail
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