ZFIN ID: ZDB-FIG-160630-30
Lovely et al., 2016 - Bmp signaling mediates endoderm pouch morphogenesis by regulating Fgf signaling in zebrafish. Development (Cambridge, England)   143(11):2000-11 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage Range: 14-19 somites to Prim-15
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 14-19 somites to Prim-15

Fig. 7

Fgf signaling activity requires Bmp. (A,B) Endodermal pouches express the Fgf signaling target etv4 at 30hpf in (A) control but not (B) Dorsomorphin-treated embryos. Lateral views, anterior to the left. (C-H) Expression of the Fgf receptors fgfr1b, fgfr3 and fgfr4 at 18hpf in control and Dorsomorphin-treated embryos. Only fgfr4 is expressed in the pharyngeal tissues and is reduced in Dorsomorphin-treated embryos (G,H, arrows). (C-F) Dorsal views, (G,H) ventral views, anterior to the left. Scale bars: 50┬Ám.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
etv4 WT control Prim-15 pharyngeal pouch ISH
WT chemical treatment: dorsomorphin Prim-15 pharyngeal pouch ISH
fgfr1b WT control 14-19 somites Not Detected pharynx ISH
WT chemical treatment: dorsomorphin 14-19 somites Not Detected pharynx ISH
fgfr3 WT control 14-19 somites Not Detected pharynx ISH
WT chemical treatment: dorsomorphin 14-19 somites Not Detected pharynx ISH
fgfr4 WT control 14-19 somites pharynx ISH
WT chemical treatment: dorsomorphin 14-19 somites pharynx ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment: dorsomorphin 14-19 somites pharynx fgfr4 expression decreased distribution, abnormal
Prim-15 pharyngeal pouch etv4 expression decreased distribution, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development