ZFIN ID: ZDB-FIG-160517-9
Banote et al., 2016 - β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner. Developmental Biology   413(1):26-38 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Anatomical Terms:
Stage Range: Bud to Prim-5

Fig. 9

Appb is expressed at 10 hpf but not in the mature Mauthner cell. In situ hybridization of appb mRNA showed stronger expression in the hindbrain at 10 hpf (A1, A2). Embryos are shown in lateral (A1) and dorsal view (A2). Arrowhead indicates the boundary between hindbrain. Co-labeling of Mauthner cell with Tg(Appb:GFP) transgenic fish line (B1-B3′) at 24 hpf. (B2) Higher magnification of boxed region in B1. (B3-B3′) Single plane lateral view across the M-cell, indicated by red vertical line in B2. Scale bars: A1, 100 µm: B1, B2, 25 µm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
appb WT standard conditions Bud hindbrain neural keel ISH
EGFP zf110Tg standard conditions Prim-5 Not Detected Mauthner neuron IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab-3A10 IHC zf110Tg standard conditions Prim-5 Mauthner neuron axon
IHC Prim-5 Mauthner neuron cell body
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 413(1), Banote, R.K., Edling, M., Eliassen, F., Kettunen, P., Zetterberg, H., Abramsson, A., β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner, 26-38, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.