ZFIN ID: ZDB-FIG-160429-1
Zhu et al., 2015 - Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling. Development (Cambridge, England)   142(3):465-76 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: 10-13 somites to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 10-13 somites to Long-pec

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
egr2b cf2Tg standard conditions Prim-5 hindbrain ISH
cf2Tg + MO1-med23 standard conditions Prim-5 hindbrain ISH
cf2Tg + MO2-med23 standard conditions Prim-5 hindbrain ISH
elavl3 cf2Tg control 10-13 somites hindbrain ISH
10-13 somites nervous system ISH
Prim-5 brain ISH
Prim-5 spinal cord ISH
cf2Tg + MO1-med23 standard conditions 10-13 somites hindbrain ISH
10-13 somites nervous system ISH
cf2Tg + MO2-med23 standard conditions 10-13 somites hindbrain ISH
10-13 somites nervous system ISH
Prim-5 brain ISH
Prim-5 spinal cord ISH
med23 WT control Prim-5 whole organism WB
WT standard conditions Prim-5 whole organism WB
WT + MO1-med23 standard conditions Prim-5 whole organism WB
WT + MO2-med23 standard conditions Prim-5 whole organism WB
YC2 cf2Tg control 14-19 somites brain IFL
Prim-5 brain IFL
Long-pec brain IFL
cf2Tg + MO1-med23 standard conditions 14-19 somites brain IFL
Prim-5 brain IFL
Long-pec brain IFL
cf2Tg + MO2-med23 standard conditions 14-19 somites brain IFL
Prim-5 brain IFL
Long-pec brain IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-med23 standard conditions Prim-5 whole organism med23 expression decreased amount, abnormal
WT + MO2-med23 standard conditions Prim-5 whole organism med23 expression decreased amount, abnormal
cf2Tg + MO1-med23 standard conditions 10-13 somites hindbrain elavl3 expression increased amount, abnormal
10-13 somites negative regulation of neurogenesis decreased occurrence, abnormal
14-19 somites brain YC2 expression increased amount, abnormal
14-19 somites negative regulation of neurogenesis decreased occurrence, abnormal
Prim-5 brain YC2 expression increased amount, abnormal
Prim-5 hindbrain egr2b expression increased amount, abnormal
Prim-5 negative regulation of neurogenesis decreased occurrence, abnormal
Long-pec brain YC2 expression decreased amount, abnormal
cf2Tg + MO2-med23 standard conditions 10-13 somites hindbrain elavl3 expression increased amount, abnormal
10-13 somites negative regulation of neurogenesis decreased occurrence, abnormal
14-19 somites brain YC2 expression increased amount, abnormal
14-19 somites negative regulation of neurogenesis decreased occurrence, abnormal
Prim-5 brain elavl3 expression increased amount, abnormal
Prim-5 brain YC2 expression increased amount, abnormal
Prim-5 hindbrain egr2b expression increased amount, abnormal
Prim-5 negative regulation of neurogenesis decreased occurrence, abnormal
Prim-5 spinal cord elavl3 expression increased amount, abnormal
Long-pec brain YC2 expression decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development