Gene
med23
- ID
- ZDB-GENE-040724-82
- Name
- mediator complex subunit 23
- Symbol
- med23 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Acts upstream of or within circulatory system development; negative regulation of neurogenesis; and pigmentation. Predicted to be located in nucleus. Predicted to be part of mediator complex and transcription regulator complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Orthologous to human MED23 (mediator complex subunit 23).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 18 | Alliance | Intellectual developmental disorder, autosomal recessive 18, with or without epilepsy | 614249 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR021629 | Mediator complex, subunit Med23 |
Domain Details Per Protein
| Protein | Length | Mediator complex, subunit Med23 |
|---|---|---|
|
UniProtKB:A0A8M9PSM3
|
1387 | |
|
UniProtKB:A0A8M2B755
|
1380 | |
|
UniProtKB:A0A8M2B7H3
|
1386 | |
|
UniProtKB:Q5RIW8
|
1376 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-med23 | monoclonal | IgG1 , k | Mouse |
|
BD Biosciences
|
2 |
Plasmids
No data available