Gene
med23
- ID
- ZDB-GENE-040724-82
- Name
- mediator complex subunit 23
- Symbol
- med23 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Involved in cardiovascular system development; negative regulation of neurogenesis; and pigmentation. Predicted to localize to mediator complex and transcription factor complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MED23 (mediator complex subunit 23).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 18 | Alliance | Intellectual developmental disorder, autosomal recessive 18, with or without epilepsy | 614249 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR021629 | Mediator complex, subunit Med23 |
Domain Details Per Protein
| Protein | Length | Mediator complex, subunit Med23 |
|---|---|---|
|
UniProtKB:A0A8M9PSM3
|
1387 | |
|
UniProtKB:A0A8M2B755
|
1380 | |
|
UniProtKB:A0A8M2B7H3
|
1386 | |
|
UniProtKB:Q5RIW8
|
1376 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-med23 | monoclonal | IgG1 , k | Mouse |
|
BD Biosciences
|
2 |
Plasmids
No data available