ZFIN ID: ZDB-FIG-150911-4
He et al., 2015 - Inflammatory signaling regulates hematopoietic stem and progenitor cell emergence in vertebrates. Blood   125(7):1098-106 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Day 4
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 4

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP la2Tg standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + MO1-myd88 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + MO1-nfkbiaa standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + MO1-tlr4bb standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
s896Tg; zf169Tg control Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg chemical treatment: JSH-23 Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + MO1-myd88 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + MO1-nfkbiaa standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + MO1-tlr4bb standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
foxn1 TU standard conditions Protruding-mouth thymic epithelium ISH
TU + MO1-myd88 standard conditions Protruding-mouth thymic epithelium ISH
TU + MO1-nfkbiaa standard conditions Protruding-mouth thymic epithelium ISH
TU + MO1-tlr4bb standard conditions Protruding-mouth thymic epithelium ISH
mCherry s896Tg; zf169Tg control Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg chemical treatment: JSH-23 Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + MO1-myd88 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + MO1-nfkbiaa standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + MO1-tlr4bb standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
myb WT standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell ISH
myd88hu3568/hu3568 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell ISH
rag1 TU standard conditions Day 4 T cell ISH
TU + MO1-myd88 standard conditions Day 4 T cell ISH
TU + MO1-nfkbiaa standard conditions Day 4 T cell ISH
TU + MO1-tlr4bb standard conditions Day 4 T cell ISH
runx1 TU control Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU chemical treatment: JSH-23 Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + MO1-myd88 standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + MO1-nfkbiaa standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + MO1-tlr4bb standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
myd88hu3568/hu3568 standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TU chemical treatment: JSH-23 Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
TU + MO1-myd88 standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Day 4 T cell decreased amount, abnormal
TU + MO1-nfkbiaa standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell increased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell increased amount, abnormal
Day 4 T cell increased amount, abnormal
TU + MO1-tlr4bb standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Day 4 T cell decreased amount, abnormal
la2Tg + MO1-myd88 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell decreased amount, abnormal
la2Tg + MO1-nfkbiaa standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell increased amount, abnormal
la2Tg + MO1-tlr4bb standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell decreased amount, abnormal
myd88hu3568/hu3568 standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell decreased amount, abnormal
s896Tg; zf169Tg chemical treatment: JSH-23 Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
s896Tg; zf169Tg + MO1-myd88 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
s896Tg; zf169Tg + MO1-nfkbiaa standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell increased amount, abnormal
s896Tg; zf169Tg + MO1-tlr4bb standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Full text @ Blood