FIGURE

Fig. 4

ID

ZDB-FIG-150910-19

Publication

Fujisawa et al., 2015 - Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Liver expansion and reduced Maid expression during chemical carcinogenesis in zebrafish.

(A) Top left: Macroscopic views of zebrafish in Group 1. Red arrow indicates a distended abdomen. Top middle: Macroscopic views of zebrafish in Group 2. Top right: Macroscopic view of a control zebrafish reared for 5 weeks in clean water and not exposed to DEN. Bottom panels show macroscopic views of (middle) livers of two DEN-treated zebrafish in Group 2 and (right) healthy control liver. (B) Western blot analysis of Maid and PCNA protein in two normal zebrafish livers and livers of 5 zebrafish subjected to 8 weeks of DEN administration. Left: Graphical representation of Western blot analysis, **, p<0.01.

Expression Data

Genes:	ccndbp1 pcna
Antibody:	Ab1-ccndbp1
Fish:	RW
Condition:	chemical treatment: N-nitrosodiethylamine
Anatomical Term:	liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	RW
Condition:	chemical treatment: N-nitrosodiethylamine
Observed In:	liver liver cholangiocarcinoma liver hepatocellular carcinoma
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One