FIGURE

Fig. S6

ID

ZDB-FIG-150507-9

Publication

Benini et al., 2015 - slc7a6os Gene Plays a Critical Role in Defined Areas of the Developing CNS in Zebrafish

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Fig. S6

Loss of function of slc7a6os leads to severe defects in MHB region.

Control (n = 37) and slc7a6os morphant embryos (n = 33) were analyzed by WISH for wnt1 gene expression. At 24 hpf expression in the midbrain-hindbrain boundary is strongly affected in morphants compared to controls (A). Two categories of phenotypes are present in morphants: a mild phenotype (B) observed in two third of the embryos and a more severe one present in the remaining third (C). Abbreviations: MHB: midbrain-hindbrain boundary.

Expression Data

Gene:	wnt1
Fish:	AB AB + MO1-slc7a6os
Knockdown Reagent:	MO1-slc7a6os
Anatomical Term:	midbrain hindbrain boundary
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-slc7a6os
Knockdown Reagent:	MO1-slc7a6os
Observed In:	midbrain hindbrain boundary midbrain-hindbrain boundary development
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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