FIGURE

Fig. 7

ID

ZDB-FIG-150311-13

Publication

Le Pabic et al., 2014 - Fat-Dachsous Signaling Coordinates Cartilage Differentiation and Polarity during Craniofacial Development

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Fig. 7

REREa interacts genetically with Fat3.

(A, B) sox9a/col2a1 expression patterns in rerea^+/+, rerea^+/- (A) and rerea^-/- (B) embryos. (C, D) Reduction in sox9a/col2a1 expression in Fat3-deficient embryos (C), but not in embryos deficient in both Fat3 and REREa (D). (E, F) Reduction in sox9a/col2a1 expression in Dchs2-deficient embryos (E) and embryos deficient in Dchs2 and REREa (F). (G) Quantification of the proportion of embryos with reduced sox9a/col2a1 expression. Scale bar = 54µm. Mc: Meckel′s; pq: palatoquadrate.

Expression Data

Genes:	col2a1a sox9a
Fish:	rerea^tb210/tb210 rerea^tb210/+ rerea^tb210/+ + MO1-dchs2 rerea^tb210/+ + MO1-fat3a rerea^tb210/tb210 + MO1-dchs2 rerea^tb210/tb210 + MO1-fat3a (all 6)
Knockdown Reagents:	MO1-dchs2 MO1-fat3a
Anatomical Terms:	Meckel's cartilage palatoquadrate cartilage
Stage:	Pec-fin

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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