FIGURE

Fig. 5

ID

ZDB-FIG-150309-10

Publication

Superina et al., 2014 - Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Convergence and extension defects are apparent in MZjek. (A,B) Representative photos of live wildtype (A; N=9) and MZjek (B; N=7) embryos at 9 SS. (C) Quantification of the angle of body axis extension over the yolk in wildtype, MZjek and Zkny (***p<0.001). (D,E) Flat-mounts of 10 SS wildtype (D; N=13) and MZjek (E; N=10) embryos stained for krox-20 (hindbrain) and myoD (somite) gene expression. (F) Quantification of the anterior–posterior extent of the myoD expression domain in wildtype versus MZjek (***p<0.001). (G) Quantification of the mediolateral extent of krox20 expression in wildtype versus MZjek (***p<0.001).

Expression Data

Genes:	egr2b myod1
Fish:	WT ugdh^m310/m310
Anatomical Terms:	hindbrain somite
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ugdh^m310/m310
Observed In:	convergent extension
Stage:	5-9 somites

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 387(2), Superina, S., Borovina, A., and Ciruna, B., Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry, 154-166, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.