ZFIN ID: ZDB-FIG-150202-18
Verleyen et al., 2014 - Orphan G-Protein Coupled Receptor 22 (Gpr22) Regulates Cilia Length and Structure in the Zebrafish Kupffer's Vesicle. PLoS One   9:e110484 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. S6

gpr22 morphants display otolith defects. Left ear with anterior to the left of zebrafish embryos at 2 dpf, injected at one cell stage with (A) water or (B, C) 0.2 mM gpr22 MO. (A) Control embryos have 2 tethered otoliths (white asterisks) at the anterior and posterior poles of the otic vesicle. In contrast, gpr22 morphants display (B) fused otoliths or (C) an increased number of otoliths, which are not correctly positioned. dpf = days post-fertilization, MO = morpholino.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-gpr22a + MO4-tp53 standard conditions Long-pec inner ear has extra parts of type otolith, abnormal
Long-pec otolith fused with otolith, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One