header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-140917-14
Apschner et al., 2014 - Pathological mineralization in a zebrafish enpp1 mutant exhibits features of Generalized Arterial Calcification of Infancy (GACI) and Pseudoxanthoma Elasticum (PXE). Disease models & mechanisms   7(7):811-22 Full text @ Dis. Model. Mech.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage: Days 7-13
PHENOTYPE:
Fish:
Observed In:
Stage: Days 7-13

Fig. 4 Expression of regulators of phosphate and biomineralization is perturbed in dgf mutants. qPCR analysis showing the relative gene expression levels of genes involved in phosphate homeostasis and biomineralization in siblings (sib) compared with those in dgf mutants, normalized to the expression of ef2a. *P≤0.05, **P≤0.01. Means ± s.e.m. are shown.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
entpd5a WT standard conditions Days 7-13 whole organism RTPCR
enpp1hu4581/hu4581 standard conditions Days 7-13 whole organism RTPCR
fgf23 WT standard conditions Days 7-13 whole organism RTPCR
enpp1hu4581/hu4581 standard conditions Days 7-13 whole organism RTPCR
phex WT standard conditions Days 7-13 whole organism RTPCR
enpp1hu4581/hu4581 standard conditions Days 7-13 whole organism RTPCR
phospho1 WT standard conditions Days 7-13 whole organism RTPCR
enpp1hu4581/hu4581 standard conditions Days 7-13 whole organism RTPCR
slc34a1a WT standard conditions Days 7-13 whole organism RTPCR
enpp1hu4581/hu4581 standard conditions Days 7-13 whole organism RTPCR
spp1 WT standard conditions Days 7-13 whole organism RTPCR
enpp1hu4581/hu4581 standard conditions Days 7-13 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
enpp1hu4581/hu4581 standard conditions Days 7-13 bone mineralization process quality, abnormal
Days 7-13 phosphate ion homeostasis process quality, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Disease models & mechanisms for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dis. Model. Mech.