Gene
phex
- ID
- ZDB-GENE-030103-2
- Name
- phosphate regulating endopeptidase homolog, X-linked
- Symbol
- phex Nomenclature History
- Previous Names
-
- wu:fx03e08
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in X-linked dominant hypophosphatemic rickets. Is expressed in lapillus. Orthologous to human PHEX (phosphate regulating endopeptidase homolog X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked dominant hypophosphatemic rickets | Alliance | Hypophosphatemic rickets, X-linked dominant | 307800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metallopeptidase, catalytic domain superfamily | Peptidase M13 | Peptidase M13, C-terminal domain | Peptidase M13, domain 2 | Peptidase M13, N-terminal domain |
|---|---|---|---|---|---|---|
|
UniProtKB:F1R6K1
|
745 | |||||
|
UniProtKB:A0A286Y855
|
727 |
Interactions and Pathways
No data available
Plasmids
No data available