Gene
fgf23
- ID
- ZDB-GENE-050201-4
- Name
- fibroblast growth factor 23
- Symbol
- fgf23 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable growth factor activity and type 1 fibroblast growth factor receptor binding activity. Acts upstream of or within calcium ion homeostasis. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in corpuscles of Stannius; gill; and kidney. Human ortholog(s) of this gene implicated in autosomal dominant hypophosphatemic rickets. Orthologous to human FGF23 (fibroblast growth factor 23).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant hypophosphatemic rickets | Alliance | Hypophosphatemic rickets, autosomal dominant | 193100 |
| Tumoral calcinosis, hyperphosphatemic, familial, 2 | 617993 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:Q5MK87
|
258 |
Interactions and Pathways
No data available
Plasmids
No data available