Gene

fgf23

ID
ZDB-GENE-050201-4
Name
fibroblast growth factor 23
Symbol
fgf23 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have growth factor activity and type 1 fibroblast growth factor receptor binding activity. Involved in calcium ion homeostasis. Predicted to localize to cytoplasm and extracellular space. Is expressed in corpuscles of Stannius and kidney. Human ortholog(s) of this gene implicated in autosomal dominant hypophosphatemic rickets. Orthologous to human FGF23 (fibroblast growth factor 23).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 8 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Lin et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fgf23 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant hypophosphatemic rickets Alliance Hypophosphatemic rickets, autosomal dominant 193100
Tumoral calcinosis, hyperphosphatemic, familial, 2 617993
Associated With fgf23 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002209 Fibroblast growth factor family
Family IPR028304 Fibroblast growth factor 23
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Fibroblast growth factor 23 Fibroblast growth factor family
UniProtKB:Q5MK87 258
UniProtKB:Q1L8M3 258
UniProtKB:Q5TLD4 243
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations