Gene

spp1

ID
ZDB-GENE-050706-97
Name
secreted phosphoprotein 1
Symbol
spp1 Nomenclature History
Previous Names
  • osteopontin (1)
  • zgc:111821
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Involved in bone development. Human ortholog(s) of this gene implicated in several diseases, including biliary atresia; coronary artery disease (multiple); disease of cellular proliferation (multiple); multiple sclerosis; and rheumatoid arthritis. Is expressed in several structures, including cranium; heart; opercular flap; osteoblast; and pectoral fin. Orthologous to human SPP1 (secreted phosphoprotein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
39 figures from 29 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Venkatesh et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spp1 Human Ortholog
No data available
Associated With spp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002038 Osteopontin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations