ZFIN ID: ZDB-GENE-040801-198
Gene Name: phosphoethanolamine/phosphocholine phosphatase 1
Gene Symbol: phospho1    Nomenclature History

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Previous Names: sb:cb839, zgc:92423 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and phosphatase activity. Predicted to be involved in regulation of bone mineralization. Is expressed in cleithrum and yolk syncytial layer. Orthologous to human PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1).
Genome Resources: Alliance (1),  Gene:100002812 (1),  Ensembl(GRCz11):ENSDARG00000008403 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2001 [cb839]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40023 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH phospho1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH phospho1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of bone mineralization (more)
    Cellular Component cellular_component (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR006384 Pyridoxal phosphate phosphatase-related
    Family IPR016965 Phosphatase PHOSPHO-type
    Homologous_superfamily IPR023214 HAD superfamily
    Homologous_superfamily IPR036412 HAD-like superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA phospho1-201 (1)    Ensembl 2098
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM phospho1 No data available
    MARKER RELATIONSHIPS
    phospho1 Contained in: [BAC] DKEY-91D10 (1) (order this)
    phospho1 Encodes: [EST] cb839 (1) (order this)
    [cDNA] MGC:92423 (1), MGC:191920 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003461 (1) 1305 bp
    Genomic GenBank:BX914211 (1) 179226 bp
    Select Tool
    Polypeptide UniProtKB:B2GQI1 (1) 279 aa
    Sequence Information (all 16)
    ORTHOLOGY for phospho1 ( Chr: 3 )
    CITATIONS (25)