FIGURE

Fig. 6

ID

ZDB-FIG-130607-12

Publication

Matsuda et al., 2013 - Lef1 regulates Dusp6 to influence neuromast formation and spacing in the zebrafish posterior lateral line primordium

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Fig. 6

Attenuation of Wnt signaling facilitates neuromast formation in fgf10 morphants. (A-L) Attenuation of Wnt signaling with IWR-1 facilitates earlier shrinking of the Wnt system, earlier establishment of effective FGFR signaling and earlier initiation of neuromast deposition in the PLLp of fgf10 morphants. lef1 expression (A-D), pea3 expression (E-H) and the neuromast deposition pattern (I-L, arrows) are shown in control morphants (A,E,I), control morphants with IWR-1 treatment (B,F,J), fgf10 morphants (C,G,K) and fgf10 morphants with IWR-1 treatment (D,H,L). For statistical analysis, see

Expression Data

Genes:	EGFP etv4 lef1
Fish:	WT WT + MO1-fgf10a + MO4-tp53 zf106Tg zf106Tg + MO1-fgf10a + MO4-tp53
Conditions:	chemical treatment: dimethyl sulfoxide chemical treatment: pharmaceutical
Knockdown Reagents:	MO1-fgf10a MO4-tp53
Anatomical Terms:	neuromast posterior lateral line primordium
Stage Range:	Prim-15 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf106Tg zf106Tg + MO1-fgf10a + MO4-tp53
Conditions:	chemical treatment: dimethyl sulfoxide chemical treatment: pharmaceutical
Knockdown Reagents:	MO1-fgf10a MO4-tp53
Observed In:	neuromast deposition
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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