FIGURE

Fig. 8

ID

ZDB-FIG-130513-2

Publication

Stoletov et al., 2013 - Role of connexins in metastatic breast cancer and melanoma brain colonization

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

The GJ inhibitor CBX inhibits breast cancer brain colonization. (A,B) Chickens were treated with (A) vehicle or (B) CBX (2.5mg/egg/day) starting 1day before tumor cell injection. Microtumor formation in the brain was assessed at the indicated days using confocal microscopy as described for Fig.6B. Insets show higher magnification (60×) of the areas outlined by the dashed squares. The brain vasculature is labeled with Rhodamine–lectin dye (red). (C) Average length of tumor-cell blood vessel contacts for 4T-1 cells from the brains of vehicle or CBX-treated chicken 6 days after injection. (D) Number and volume of microtumors per chicken brain induced by 4T-1 tumor cells for vehicle or CBX-treated chickens 6 days after injection. Scale bars: 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.