Fig. 2
- ID
- ZDB-FIG-130123-38
- Publication
- Clanton et al., 2013 - Fgf signaling governs cell fate in the zebrafish pineal complex
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Loss of Fgf signaling results in fewer parapineal cells. (A,B) Dorsal views of WT and fgf8ax15 mutant zebrafish embryos labeled with gfi-1.2 (parapineal cells; black arrowheads). (C,D) Dorsal views showing expression of gfi-1.2 (black arrowheads) in WT larvae at 52 hpf that were treated between 24 and 30 hpf with either DMSO or SU5402. In A-D, dashed line encircles the pineal complex anlage. (E) fgf8ax15 mutants displayed a significant reduction in parapineal cell number compared with WT (***P=<0.0005 by t-test). (F) Reductions in parapineal cell numbers were observed in embryos treated with SU5402, particularly for 18-24 hpf and 24-30 hpf treatments (***P<0.0005 by t-test). Error bars represent s.e.m. Scale bar: 25 μm. |
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Stage: | Long-pec |
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Stage Range: | 14-19 somites to Day 4 |