FIGURE

Fig. 7

ID

ZDB-FIG-130102-7

Publication

Vemaraju et al., 2012 - A spatial and temporal gradient of fgf differentially regulates distinct stages of neural development in the zebrafish inner ear

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Fig. 7

Normal axial patterning in fgf5 morphants.

(A-H) Expression of regional patterning markers in control embryos (A–D) and fgf5 morphants (E-H). Expression of pax5 (A, E) and pou3f3b (B, F) labels anterior and posterior regions, respectively. Expression of otx1a (C, G) and dlx3b (D, H) labels ventromedial and dorsolateral regions, respectively. The otic vesicle is outlined. Images show dorsolateral views with anterior to the left. (I) The total number of hair cells in the utricular (ut) and saccular (sac) maculae of control embryos and fgf5 morphants at 32 hpf. Data were obtained by counting GFP-positive hair cells (mean of total number ± standard deviation) in the sensory epithelia of brn3c:Gfp transgenic embryos. Data show means and standard deviations from 20 specimens each. Differences between control and experimental specimens were not statistically significant (p = 0.16 for the utricle, p = 0.67 for the saccule) based on Student′s t tests.

Expression Data

Genes:	dlx3b otx2a pax5 pou3f3b
Fish:	WT WT + MO3-fgf5
Knockdown Reagent:	MO3-fgf5
Anatomical Terms:	otic vesicle anterior region otic vesicle dorso-lateral region otic vesicle posterior region otic vesicle ventro-medial region
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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