FIGURE

Fig. S3

ID
ZDB-FIG-121205-3
Publication
Blaker-Lee et al., 2012 - Zebrafish homologs of 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes
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Fig. S3

Pigmentation is abnormal in LOF embryos. Pigment cells were observed after LOF, at 48 hpf, by brightfield imaging. Rostral and midline cells were specifically scored as a measure of normal melanocyte migration. (A-I) dorsal views. Genes targeted for LOF by MO injection are indicated above each set of panels. Red arrowhead, no rostral pigment cells; red arrow, no midline pigment cells; scale bar, 150 μM. Average of 35 embryos assayed per gene, over 2-4 independent experiments, 70-100% affected compared to control MO-injected embryos.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
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