ZFIN ID: ZDB-FIG-121030-23
Mef2c protein is downregulated in mef2ca mutants.
Confocal stacks of Mef2ca/cb immunodetection (Anaspec, red in A-C) and DAPI (blue, A and C) in wildtype and mef2ca mutant embryos. A. Reaction with Mef2c antibody is strong in nuclei of differentiated slow muscle fibres in the somite (left panel), but is missing from the PSM (right panel), and from cranial ganglia indicating that the antibody is not crossreacting with Mef2d and Mef2a protein, respectively. B and C. Anti-Mef2c antibody reacts weakly in CMs of mef2cab1086 mutant embryos (B), but is absent from nuclei in the myotome of the somites (C). Scale = 50 μm (except in A=100 μm).
Gene Expression DetailsNo data available
Antibody Labeling Details
Phenotype Details No data available
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Reprinted from Developmental Biology, 369(2), Hinits, Y., Pan, L., Walker, C., Dowd, J., Moens, C.B., and Hughes, S.M., Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation, 199-210, Copyright
(2012) with permission from Elsevier.
Full text @ Dev. Biol.