FIGURE

Fig. 2

ID

ZDB-FIG-120810-56

Publication

Lee et al., 2012 - Disruption of the folate pathway in zebrafish causes developmental defects

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Fig. 2

Wild type expression data for folate pathway transcripts. A) RT-PCR analysis of 11 embryonic stages within the first 72 hours of development indicates that genes involved in the folate pathway are generally maternally loaded transcripts that are expressed throughout early development. B) in situ hybridization for these 16 genes at 24 hpf shows that many are globally expressed with enrichment in anterior neural tissues including tectonic and retinal staining. Specific somatic staining is seen in mat1a, mat2aa, mat2ab, and mthfr. YSL staining is also observed in mat1a and mthfd1b. Embryos in lateral view.

Expression Data

Genes:	dhfr mat1a mat2aa mat2ab mat2al mat2b mthfd1a mthfd1b mthfd1l mthfd2 mthfd2l mthfr mtr slc25a32a slc25a32b tyms
Fish:	AB/TU
Anatomical Terms:	anterior neural tube optic cup somite whole organism yolk syncytial layer
Stage Range:	4-cell to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.