ZFIN is now using GRCz12tu for Genomic Data
Gene
mat2aa
- ID
- ZDB-GENE-030131-2049
- Name
- methionine adenosyltransferase 2Aa
- Symbol
- mat2aa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable methionine adenosyltransferase activity. Acts upstream of or within cardiac muscle cell development. Predicted to be part of methionine adenosyltransferase complex. Predicted to be active in cytosol. Is expressed in anterior neural tube; epiphysis; heart; optic cup; and somite. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MAT2A (methionine adenosyltransferase 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56664 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022631 | S-adenosylmethionine synthetase, conserved site |
| Domain | IPR022628 | S-adenosylmethionine synthetase, N-terminal |
| Domain | IPR022629 | S-adenosylmethionine synthetase, central domain |
| Domain | IPR022630 | S-adenosylmethionine synthetase, C-terminal |
| Family | IPR002133 | S-adenosylmethionine synthetase |
| Homologous_superfamily | IPR022636 | S-adenosylmethionine synthetase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | S-adenosylmethionine synthetase | S-adenosylmethionine synthetase, central domain | S-adenosylmethionine synthetase, conserved site | S-adenosylmethionine synthetase, C-terminal | S-adenosylmethionine synthetase, N-terminal | S-adenosylmethionine synthetase superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QYU7 | InterPro | 395 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mat2aa-202
(1)
|
Ensembl | 1,843 nt | ||
| ncRNA |
mat2aa-002
(1)
|
Ensembl | 862 nt | ||
| ncRNA |
mat2aa-004
(1)
|
Ensembl | 551 nt | ||
| ncRNA |
mat2aa-006
(1)
|
Ensembl | 766 nt | ||
| ncRNA |
mat2aa-007
(1)
|
Ensembl | 643 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers