Gene

mat2aa

ID

ZDB-GENE-030131-2049

Name

methionine adenosyltransferase 2Aa

Symbol

mat2aa Nomenclature History

Previous Names

mat2a (1)
fd12a12
si:ch73-340n8.1
wu:fb95e01
wu:fd12a12 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable methionine adenosyltransferase activity. Acts upstream of or within cardiac muscle cell development. Predicted to be part of methionine adenosyltransferase complex. Predicted to be active in cytosol. Is expressed in anterior neural tube; epiphysis; heart; optic cup; and somite. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MAT2A (methionine adenosyltransferase 2A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56664 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mat2aa Human Ortholog

No data available

Associated With mat2aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR022631	S-adenosylmethionine synthetase, conserved site
Domain	IPR022628	S-adenosylmethionine synthetase, N-terminal
Domain	IPR022629	S-adenosylmethionine synthetase, central domain
Domain	IPR022630	S-adenosylmethionine synthetase, C-terminal
Family	IPR002133	S-adenosylmethionine synthetase
Homologous_superfamily	IPR022636	S-adenosylmethionine synthetase superfamily

Domain Details Per Protein

Protein	Length	S-adenosylmethionine synthetase	S-adenosylmethionine synthetase, central domain	S-adenosylmethionine synthetase, conserved site	S-adenosylmethionine synthetase, C-terminal	S-adenosylmethionine synthetase, N-terminal	S-adenosylmethionine synthetase superfamily
UniProtKB:F1QYU7 InterPro	395

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mat2aa-202 (1) Ensembl	Ensembl	1,843 nt	Select Tool ZFIN BLAST
ncRNA	mat2aa-002 (1) Ensembl	Ensembl	862 nt	Select Tool ZFIN BLAST
ncRNA	mat2aa-004 (1) Ensembl	Ensembl	551 nt	Select Tool ZFIN BLAST
ncRNA	mat2aa-006 (1) Ensembl	Ensembl	766 nt	Select Tool ZFIN BLAST
ncRNA	mat2aa-007 (1) Ensembl	Ensembl	643 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations