FIGURE

Fig. 7

ID
ZDB-FIG-120725-28
Publication
Wythe et al., 2011 - Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish
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Fig. 7

Ca2+ transient duration is altered following loss of hadp1. (A-H) Optical mapping and quantification of Ca2+ transients in the embryonic zebrafish heart. (A) Representative images of the mean Ca2+ transient amplitude following optical mapping, using the ratiometric dye Fura-2, in control and hadp1 morphant hearts. The red box denotes an example of the pixel areas that were sampled for quantification of ventricular transients. The far-right scale indicates the transient amplitude intensity. (B) Representative traces of Ca2+ transients from single sites in the atrium and ventricle of control (black) and hadp1 morphants (red). (C-E) Quantification of the atrial diastolic Ca2+ (C), transient amplitude (D) and transient duration (E). (F-H) Quantification of the ventricular diastolic Ca2+ (F), transient amplitude (G) and transient duration (H).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.