FIGURE

Fig. 5

ID

ZDB-FIG-120315-49

Publication

Simmons et al., 2012 - Mutation of pescadillo Disrupts Oligodendrocyte Formation in Zebrafish

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Fig. 5

Loss of pes function disrupts progression of spinal cord cells through the cell cycle.

(A) The time required to progress from S-phase to M-phase in the spinal cord is shown by the ratio of PH-3⁺/BrdU⁺ to total PH-3⁺ cells at the indicated time points after a BrdU pulse. (B) The length of S-phase in the spinal cord is shown by the ratio of BrdU⁺/EdU⁺ cells to total BrdU⁺ cells at the indicated time points after a BrdU pulse. Wild-type (blue) and pes^{166 -/-} (red) are shown. (C,D) Transverse sections through spinal cords of 4 dpf wild-type (C) and mutant (D) larvae processed for in situ RNA hybridization showing the expression of the neural precursor marker sox2.

Expression Data

Gene:	sox2
Fish:	AB pes^vu166/vu166 (AB)
Anatomical Terms:	spinal cord neurectodermal cell spinal cord oligodendrocyte
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pes^vu166/vu166 (AB)
Observed In:	mitotic S phase neurectodermal cell oligodendrocyte oligodendrocyte differentiation
Stage:	Day 4

Phenotype Detail

Acknowledgments

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