ZFIN Image: Simmons et al., 2012, Fig. 5

Image

Figure Caption

Fig. 5

Loss of pes function disrupts progression of spinal cord cells through the cell cycle.

(A) The time required to progress from S-phase to M-phase in the spinal cord is shown by the ratio of PH-3⁺/BrdU⁺ to total PH-3⁺ cells at the indicated time points after a BrdU pulse. (B) The length of S-phase in the spinal cord is shown by the ratio of BrdU⁺/EdU⁺ cells to total BrdU⁺ cells at the indicated time points after a BrdU pulse. Wild-type (blue) and pes^{166 -/-} (red) are shown. (C,D) Transverse sections through spinal cords of 4 dpf wild-type (C) and mutant (D) larvae processed for in situ RNA hybridization showing the expression of the neural precursor marker sox2.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One