ZFIN ID: ZDB-FIG-111129-24
Goudevenou et al., 2011 - Def6 Is Required for Convergent Extension Movements during Zebrafish Gastrulation Downstream of Wnt5b Signaling. PLoS One   6(10):e26548 Full text @ PLoS One
Anatomical Terms:
Stage Range: 8-cell to Protruding-mouth

Fig. 1

Zebrafish def6 is dynamically expressed during development.

(A) Schematic representation of the def6 protein domain arrangement consisting of an N-terminal putative Ca2+-binding EF-hand domain followed by a def6/swap-70 homology (DSH), a pleckstrin-homology (PH) domain and a C-terminal Dbl-homology-like (DHL) domain. (B) Sequence identity and similarity of the various def6 domains between different species as indicated. (C-E) Def6 is ubiquitously expressed at the (C) 8-cell stage, (D) 40% epiboly and (E) 80% epiboly stages. (F) At 24hpf, def6 transcripts are found in the developing brain, somite boundaries and tail. (G) The expression pattern of def6 becomes more restricted at 3dpf where mRNA can be detected in the pharyngeal arches, medial and pectorial fins and anterior and posterior neuromasts of the lateral line.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
def6a WT standard conditions 8-cell to 75%-epiboly whole organism ISH
Prim-5 brain ISH
Prim-5 post-vent region ISH
Prim-5 somite border ISH
Protruding-mouth anterior lateral line neuromast ISH
Protruding-mouth median fin ISH
Protruding-mouth pectoral fin ISH
Protruding-mouth pharyngeal arch ISH
Protruding-mouth posterior lateral line neuromast ISH
Antibody Labeling Details No data available
Phenotype Details No data available
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