Gene
def6a
- ID
- ZDB-GENE-040426-1246
- Name
- DEF6 guanine nucleotide exchange factor a
- Symbol
- def6a Nomenclature History
- Previous Names
-
- zgc:63721 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Involved in cell migration involved in gastrulation and convergent extension involved in gastrulation. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including female organism; fin; lateral line; post-vent region; and somite border. Orthologous to human DEF6 (DEF6 guanine nucleotide exchange factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Immunodeficiency 87 and autoimmunity | 619573 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-hand domain pair | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|
|
UniProtKB:Q7SYB5
|
612 | |||
|
UniProtKB:A0A8M6Z7K3
|
631 |
Interactions and Pathways
No data available
Plasmids