FIGURE

Fig. 8

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ZDB-FIG-111128-24

Publication

Choe et al., 2011 - A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center

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Fig. 8

Combined loss of ppp1r14al and fgf8 function leads to disruption of the r4 signaling center. Uninjected (A, E, I), fgf8 MO-injected (B, F, J), ppp1r14al MO-injected (C, G, K) or fgf8 + ppp1r14al MO-injected embryos (D, H, L) were assayed for expression of krox20 (A–D), pea3 (E–H) or valentino (I–L) by in situ hybridization. All embryos are dorsal views at 11hpf with anterior to the left.

Expression Data

Genes:	egr2b etv4 mafba
Fish:	WT + MO1-ppp1r14ab WT + MO5-fgf8a WT + MO1-ppp1r14ab + MO5-fgf8a
Knockdown Reagents:	MO1-ppp1r14ab MO5-fgf8a
Anatomical Terms:	hindbrain neural keel midbrain hindbrain boundary neural keel presumptive rhombomere 3 presumptive rhombomere 5 presumptive rhombomere 6
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 358(2), Choe, S.K., Zhang, X., Hirsch, N., Straubhaar, J., and Sagerström, C.G., A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center, 356-67, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.