Gene

mafba

ID
ZDB-GENE-980526-515
Name
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
Symbol
mafba Nomenclature History
Previous Names
  • mafb
  • MafB (1)
  • kr
  • kreisler
  • krml (1)
  • val
  • valentino
  • wu:fc22d11 (1)
  • wu:fj82a09 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hindbrain development; lymphangiogenesis; and pronephric glomerulus development. Predicted to localize to nucleus. Is expressed in several structures, including hindbrain; hindbrain neural keel; neural plate; renal system; and vein. Human ortholog(s) of this gene implicated in Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Orthologous to human MAFB (MAF bZIP transcription factor B).
Genome Resources
Note
None
Expression
All Expression Data
65 figures from 52 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
21 figures from 14 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mafba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
multicentric carpotarsal osteolysis syndrome Alliance Multicentric carpotarsal osteolysis syndrome 166300
Duane retraction syndrome 3 617041
Associated With mafba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004826 Basic leucine zipper domain, Maf-type
Domain IPR004827 Basic-leucine zipper domain
Domain IPR013592 Maf transcription factor, N-terminal
Family IPR024874 Transcription factor Maf family
Family IPR028571 Transcription factor MafB
Homologous_superfamily IPR008917 Transcription factor, Skn-1-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Basic-leucine zipper domain Basic leucine zipper domain, Maf-type Maf transcription factor, N-terminal Transcription factor MafB Transcription factor Maf family Transcription factor, Skn-1-like, DNA-binding domain superfamily
UniProtKB:A0A2U3TVD3 397
UniProtKB:Q98UK5 356
Transcripts
Genome Browsers
No data available
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations