FIGURE

Fig. 7

ID

ZDB-FIG-111014-18

Publication

Hammond et al., 2011 - Fgf and Hh signalling act on a symmetrical pre-pattern to specify anterior and posterior identity in the zebrafish otic placode and vesicle

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Treatment of smo^?/? embryos with SU5402 from 10 to 20S leads to a loss of anterior and posterior otic character. Ears of smo^?/? and sibling zebrafish embryos treated with 10 μM SU5402 and DMSO, respectively, from 10 to 20S. (A,B) Anti-acetylated tubulin antibody stain marking the kinocilia of the first-forming hair cells (arrows). (C-J) FITC-phalloidin stain marking cell outlines and stereociliary bundles of the sensory hair cells. (C-F) Views of the whole vesicle. (G,H) Medial views showing the maculae. (I,J) Lateral views showing the cristae. (K-N) Inner ears of live embryos. Arrows indicate otoliths. cp, semicircular canal projection tissue. (O-T) In situ hybridisation to anterior and posterior otic markers. Dots delineate the otic vesicle in O and P. O,P,S,T: Dorsal views; anterior to left, medial to top. A-N,Q,R: Lateral views; anterior to left, dorsal to top. Scale bars: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development