FIGURE

Fig. 6

ID

ZDB-FIG-111014-17

Publication

Hammond et al., 2011 - Fgf and Hh signalling act on a symmetrical pre-pattern to specify anterior and posterior identity in the zebrafish otic placode and vesicle

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Fig. 6

Altering Fgf and Hh signalling in the embryo does not affect otic expression of ptc1 and pea3, respectively. (A-H) ptc1 expression in hsp70:fgf3 compared with wild-type sibling zebrafish embryos heat-shocked at 10S, and in 10 μM SU5402-treated embryos compared with control DMSO-treated embryos treated from 10 to 20S. (I-P) pea3 expression in otic vesicles of ptc1^-/-;ptc2^-/- and smo^-/- embryos compared with siblings. (Q,R) ptc1 expression in smo^-/- and ptc1^-/-;ptc2^-/-embryos. (S,T) pea3 expression in 10 μM SU5402-treated and in hsp70:fgf3 embryos heat-shocked at 10S. A-H,Q,R: Dorsal views; anterior to left, lateral to top. I-P,S,T: Lateral views; anterior to left, dorsal to top. Dotted lines delineate otic vesicle outlines. Bracket in K marks low-level pea3 expression, lost from 21S ptc1;ptc2^-/- embryos (bracket, L).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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